By Sharafudheen K. Chakkolayil, audiologist at Mafraq hospital and student of the Master in Clinical Audiology and Hearing Therapy 


This cross sectional study is focused on finding P300 response by changing the interstimulus interval (Gross and fine discrimination of signal) in 50 subjects with learning disabilities.
P300 recording on these ears produced long latency and reduced amplitude.
Results shows in gross and fine discrimination of signal, the latency of the P300 response increases and the amplitude decreases as the Inter-stimulus Interval (ISI) decreases. Among gender description, latency of both gross and fine discrimination of signal, female (Gross mean 408 with SD of 20.99 and fine mean 443.92 with SD of 31.06) appeared better P300 as compared to male (Gross mean 436.16 with SD of 31.99 and fine mean 459.60 with SD of 29.95). Learning disabilities individuals show auditory or cortical processing difficulty, and they needed longer inter stimulus intervals to separate two sounds than did normal individuals.

Download the full Research Work: Sharafudheen K. Chakkolayil (2017). A Study of Late Auditory Event Related Potentials Related to P300 Responses in Individuals with Learning Disabilities. SAERA




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